Endocrine Abstracts

Introduction: Cystic prolactinomas are considered resistant to volume depletion by dopamine agonists (DAs). Because of the effectiveness and tolerability, dopamine agonists (DAs) are the first line therapies in prolactinoma and reduce tumor mass as well as prolactin levels in most of all patients. Rathke’s cleft cysts, craniopharyngiomas and arachnoid cysts are differential diagnoses to keep in mind. DAs resistance or intolerance, psychiatric disorders associated with dop...

Background: Enviromental factors such as life style changes and dieatary factors become more important on the background of coronary artery disease (CAD). The thiols were the main part of the non-enzymatic antioxidant system in the body and they are the first defensive molecules in elimination of oxidant agents. As a result, thiol levels may be an earlier indicator for CAD. There is limited data on the relation of dietary factors with thiol/disulfide homeostasis in patients wi...

Background: Despite the efforts to reduce smoking, unfortunately there is a common belief in society to avoid smoking cessation or quitting smoking for weight control. As well as many negative effects of smoking, people continue to smoke instead of diet and life change. Nicotine plus high fat diet (HFD) induces intramyocellular lipid accumulation and mitochondrial abnormalities in obese mice. There is limited data in the relation of dietary fat content and metabolic syndrome i...

Diabetes is one of the risk factors for Achilles tendon rupture. Tendon thickening and impaired collagen organization have been reported in diabetic patients in small studies. In this report, we present the rupture of the Achilles tendon in a female patient with poorly controlled diabetes mellitus and diabetic neuropathy. A 52-years-old woman with a medical history of diabetes treated by intensive insulin therapy, developed pain in the right heel without previous trauma. The p...

Introduction: Autoimmune Polyglandular Syndrome (APS) is a very rare endocrinopaty, characterized by the coexistence of at least two glandular autoimmune mediated diseases. In this case a patient presented with hyperpigmentation of the whole body, significant weight loss for last 6 months.Case: A-49 year old male were refered to our deparment with loss of appetite, fatigue, nausea, weight loss and with marked buccal pigmentation. Blood pressure was 80/50...

: In this paper we present an 18-year-old patient with Klinefelter syndrome who has taurodontism. Klinefelter syndrome is the most common abnormality of sex chromosomes. It is characterized by hypogonadism, gynaecomastia, azoospermia or oligospermia, and increased levels of gonadotropins. Associated medical disorders can be categorized as follows; cancer, autoimmune disorders, intellectuel and psychiatric disorder, osteoporosis, endocrine disorders, venous disease and taurodon...

Aim: We aimed to examine the relationship between the healthy eating index (HEI) and steroidogenesis in polycystic ovary syndrome (PCOS) patients and healthy controls.Materials and Methods: In addition to demographic records and routine biochemical tests, HEI was calculated from three-day nutritional records in the Bebis program. Adrenal steroidogenesis panel was measured by LCMS.Results: The study included 50 women with PCOS and 4...

Introduction: Ornithine transcarbamylase deficiency (OTCD) is a urea cycle disorder that causes the accumulation of ammonia, which can lead to neurocognitive problems in patients1. Here we report a 21-year-old man who was diagnosed with OTCD during investigation for secondary osteoporosis.Case: The patient applied to the Endocrinology department complaining of widespread muscle-joint pain, shortening in height, nausea/vomiting attacks followed...

Pentraxin 3 (PTX3) is produced from several cell types in case of inflammation. PTX3 has been investigated in several autoimmune diseases. As Hashimoto disease is an autoimmune disease of thyroid, we investigated the role of PTX3 levels in patients with Hashimoto disease.Objective: The aim of this study was to investigate the relationship between PTX3 and autoimmune thyroiditis.Methods: The study subjects were classified as four gr...

Objective: SAGIT, a new instrument designed for therapeutic decision, is not routinely used yet. While the medical treatment was mostly planned according to disease activity by hormonal evaluation, the therapeutic decision has tried to be standardized with the SAGIT instrument. The aim of this study is to reassess the therapeutic decisions by clinicians in the management of acromegaly according to the SAGIT instrument.Material and Method: This multicente...